download XCode and build tools from Apple dev centre (FREE)
download compile and install LibUSB 1.0.8 from lib usb org
cd libusb.*
./configure
make
sudo make install
download latest OSCAM from the public SVN repo
use this modified Makefile to compile oscam latest on Mac OSX 10.6 snow leopard x64
make
this will put the compiled application in ./Distribution/